I don't know well MVC3 but you can set a custom header for all request from AngularJS.
Then on server side you just have to get this header and do what you want with request from angular.
To have custom header in AngularJS just do this :
angular.module('myModule', [])
.config(['$httpProvider', function($httpProvider) {
$httpProvider.defaults.headers.common["FROM-ANGULAR"] = "true";
}])
For use the X-Requested-With you have to do this too :
$httpProvider.defaults.headers.common["X-Requested-With"] = 'XMLHttpRequest';
It's not set by default anymore because a lot part of the community have to delete this header to enable CORS request
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