Comments are normally stripped out during preprocessing, so the compiler itself never sees them at all.
They can (and normally do) slow compilation a little though--the preprocessor has to read through the entire comment to find its end (so subsequent code will be passed through to the compiler. Unless you include truly gargantuan comments (e.g., megabytes) the difference probably won't be very noticeable though.
Although I've never seen (or heard of) a C or C++ compiler that did it, there have been compilers (e.g., for Pascal) that used specially formatted comments to pass directives to the compiler. For example, Turbo Pascal allowed (and its successor probably still allows) the user to turn range checking on and off using a compiler directive in a comment. In this case, the comment didn't (at least in the cases of which I'm aware) generate any machine code itself, but it could and did affect the machine code that was generated for the code outside the comment.
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