Use a boolean for ordering to put them first explicitly. Then you can order each of the groups separately:
ORDER BY (wp_postmeta.meta_value+0 > 20210126) DESC, -- put the bigger ones first
(CASE WHEN wp_postmeta.meta_value+0 > 20210126 THEN wp_postmeta.meta_value+0 END) ASC,
wp_postmeta.meta_value+0 DESC
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