Maybe you could union the rows and delete them at once? Something like this (untested).
Dim myRow As Range
Dim toDelete As Range
For i = 2 To 500
If Worksheets("Sales").Cells(i, 3).Value > -100 Then
Set myRow = Worksheets("Sales").Rows(i)
If toDelete Is Nothing Then
Set toDelete = myRow
Else
Set toDelete = Union(toDelete, myRow)
End If
End If
Next i
If Not toDelete Is Nothing Then _
toDelete.Delete
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