vb.net - IsNothing versus Is Nothing

Question

Does anyone here use VB.NET and have a strong preference for or against using IsNothing as opposed to Is Nothing (for example, If IsNothing(anObject) or If anObject Is Nothing...)? If so, why?

EDIT: If you think they're both equally acceptable, do you think it's best to pick one and stick with it, or is it OK to mix them?

Answer 1

If you take a look at the MSIL as it's being executed you'll see that it doesn't compile down to the exact same code. When you use IsNothing() it actually makes a call to that method as opposed to just evaluating the expression.

The reason I would tend to lean towards using "Is Nothing" is when I'm negating it becomes "IsNot Nothing' rather than "Not IsNothing(object)" which I personally feel looks more readable.