I just want to put in a word of warning: please very carefully pick your clustered index! Every "regular" data table ought to have a clustered index, since having a clustered index does indeed speed up a lot of operations - yes, speed up, even inserts and deletes! But only if you pick a good clustered index.
It's the most replicated data structure in your SQL Server database. The clustering key will be part of each and every non-clustered index on your table, too.
You should use extreme care when picking a clustering key - it should be:
narrow (4 bytes ideal)
unique (it's the "row pointer" after all. If you don't make it unique SQL Server will do it for you in the background, costing you a couple of bytes for each entry times the number of rows and the number of nonclustered indices you have - this can be very costly!)
static (never change - if possible)
ideally ever-increasing so you won't end up with horrible index fragmentation (a GUID is the total opposite of a good clustering key - for that particular reason)
it should be non-nullable and ideally also fixed width - a varchar(250)
makes a very poor clustering key
Anything else should really be second and third level of importance behind these points ....
See some of Kimberly Tripp's (The Queen of Indexing) blog posts on the topic - anything she has written in her blog is absolutely invaluable - read it, digest it - live by it!
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