It is possible, if you don't use anonymous callbacks:
var $elt = $(...);
function clickHandler1(event){...}
function clickHandler2(event){...}
// bind both
$elt.click(clickHandler1);
$elt.click(clickHandler2);
// unbind just the first
$elt.unbind('click', clickHandler1);
A wild Demo appeared!
See also: .unbind()
docs.
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