Yes you can. Here's an example from Keras's docs. You zip together two generators seeded with the same seeds and the fit_generator them.
https://keras.io/preprocessing/image/
# we create two instances with the same arguments
data_gen_args = dict(featurewise_center=True,
featurewise_std_normalization=True,
rotation_range=90.,
width_shift_range=0.1,
height_shift_range=0.1,
zoom_range=0.2)
image_datagen = ImageDataGenerator(**data_gen_args)
mask_datagen = ImageDataGenerator(**data_gen_args)
# Provide the same seed and keyword arguments to the fit and flow methods seed = 1
image_datagen.fit(images, augment=True, seed=seed)
mask_datagen.fit(masks, augment=True, seed=seed)
image_generator = image_datagen.flow_from_directory(
'data/images',
class_mode=None,
seed=seed)
mask_generator = mask_datagen.flow_from_directory(
'data/masks',
class_mode=None,
seed=seed)
# combine generators into one which yields image and masks
train_generator = zip(image_generator, mask_generator)
model.fit_generator(
train_generator,
samples_per_epoch=2000,
nb_epoch=50)
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