Yes. According to apple's policy , your application must supports IPV6. so, please check your application supports IPV6. Supporting IPv6 in iOS 9
To test, if your application supports IPV6 or not please check this ,
Supporting IPv6 DNS64/NAT64 Networks
To check with creating follow this steps , which indicate on apple's page .
To set up a local IPv6 Wi-Fi network using your Mac
1) Make sure your Mac is connected to the Internet(with ethernet), but not through Wi-Fi.
2) Launch System Preferences from your Dock, LaunchPad, or the Apple menu.
3) Press the Option key and click Sharing. Don’t release the Option key yet. (don't forget to press option key)
4)Select Internet Sharing in the list of sharing services.
5)Release the Option key.
6)Select the Create NAT64 Network checkbox.
7)Choose the network interface that provides your Internet connection, such as Thunderbolt Ethernet or Only Ethernet.
8)Select the Wi-Fi checkbox.
9)Click Wi-Fi Options, and configure the network name and security options for your network.
10) Select the Internet Sharing checkbox to enable your local network.
11)When prompted to confirm you want to begin sharing, click Start
12) Now your mac mini is working as a hotspot and useing IPv6 NAT64 network
(looks like above image when hotspot created)
Now connect your iphone with your mac mini's hotspot. and Test your Application it's working properly or not.
I hope this answer is helpful you.
Edit :- Don't forget to add below frameworks.
1) WebKit
2) CFNetwork
You will find all the information on this link related to ipv6 policy. Supporting IPv6 DNS64/NAT64 Networks