Private Sub textBox1_KeyDown(ByVal sender As Object, ByVal e As System.Windows.Forms.KeyEventArgs) Handles textBox1.KeyDown
    ' Determine whether the key entered is the F1 key. If it is, display Help.
    If e.KeyCode = Keys.F1 AndAlso (e.Alt OrElse e.Control OrElse e.Shift) Then
        ' Display a pop-up Help topic to assist the user.
        Help.ShowPopup(textBox1, "Enter your name.", New Point(textBox1.Bottom, textBox1.Right))
    ElseIf e.KeyCode = Keys.F2 AndAlso e.Modifiers = Keys.Alt Then
        ' Display a pop-up Help topic to provide additional assistance to the user.
        Help.ShowPopup(textBox1, "Enter your first name followed by your last name. Middle name is optional.", _
             New Point(textBox1.Top, Me.textBox1.Left))
    End If
End Sub

Private Sub treeView1_KeyDown(sender As Object, _
  e As KeyEventArgs) Handles treeView1.KeyDown
   ' If the 'Alt' and 'E' keys are pressed,
   ' allow the user to edit the TreeNode label. 
   If e.Alt And e.KeyCode = Keys.E Then
      treeView1.LabelEdit = True
      ' If there is a TreeNode under the mouse cursor, begin editing. 
      Dim editNode As TreeNode = treeView1.GetNodeAt( _
        treeView1.PointToClient(System.Windows.Forms.Control.MousePosition))
      If (editNode IsNot Nothing) Then
         editNode.BeginEdit()
      End If
   End If
End Sub

Private Sub treeView1_AfterLabelEdit(sender As Object, _
  e As NodeLabelEditEventArgs) Handles treeView1.AfterLabelEdit
   ' Disable the ability to edit the TreeNode labels.
   treeView1.LabelEdit = False
End Sub

' Boolean flag used to determine when a character other than a number is entered.
 Private nonNumberEntered As Boolean = False


 ' Handle the KeyDown event to determine the type of character entered into the control.
 Private Sub textBox1_KeyDown(sender As Object, e As System.Windows.Forms.KeyEventArgs) _
      Handles textBox1.KeyDown
     ' Initialize the flag to false.
     nonNumberEntered = False
   
     ' Determine whether the keystroke is a number from the top of the keyboard.
     If e.KeyCode < Keys.D0 OrElse e.KeyCode > Keys.D9 Then
         ' Determine whether the keystroke is a number from the keypad.
         If e.KeyCode < Keys.NumPad0 OrElse e.KeyCode > Keys.NumPad9 Then
             ' Determine whether the keystroke is a backspace.
             If e.KeyCode <> Keys.Back Then
                 ' A non-numerical keystroke was pressed. 
                 ' Set the flag to true and evaluate in KeyPress event.
                 nonNumberEntered = True
             End If
         End If
     End If
     'If shift key was pressed, it's not a number.
     If Control.ModifierKeys = Keys.Shift Then
         nonNumberEntered = true
     End If
 End Sub


 ' This event occurs after the KeyDown event and can be used 
 ' to prevent characters from entering the control.
 Private Sub textBox1_KeyPress(sender As Object, e As System.Windows.Forms.KeyPressEventArgs) _
     Handles textBox1.KeyPress
     ' Check for the flag being set in the KeyDown event.
     If nonNumberEntered = True Then
         ' Stop the character from being entered into the control since it is non-numerical.
         e.Handled = True
     End If
 End Sub