Private Sub RemoveTables()
   ' Set the name of the table to test for and remove.
   Dim name As String = "Suppliers"

   ' Presuming a DataGrid is displaying more than one table, get its DataSet.
   Dim thisDataSet As DataSet = CType(DataGrid1.DataSource, DataSet)
   Dim tablesCol As DataTableCollection = thisDataSet.Tables
   If tablesCol.Contains(name) _
   And tablesCol.CanRemove(tablesCol(name)) Then 
      tablesCol.Remove(name)
   End If
End Sub

Public Sub Main
DataTableCollectionCanRemove
End Sub

Public Sub DataTableCollectionCanRemove()
    ' create a DataSet with two tables
    Dim dataSet As New DataSet()

    ' create Customer table
    Dim customersTable As New DataTable("Customers")
    customersTable.Columns.Add("customerId", _
        System.Type.GetType("System.Integer")).AutoIncrement = True
    customersTable.Columns.Add("name", _
        System.Type.GetType("System.String"))
    customersTable.PrimaryKey = New DataColumn() _
        {customersTable.Columns("customerId")}

    ' create Orders table
    Dim ordersTable As New DataTable("Orders")
    ordersTable.Columns.Add("orderId", _
        System.Type.GetType("System.Integer")).AutoIncrement = True
    ordersTable.Columns.Add("customerId", _
        System.Type.GetType("System.Integer"))
    ordersTable.Columns.Add("amount", _
        System.Type.GetType("System.Double"))
    ordersTable.PrimaryKey = New DataColumn() _
        {ordersTable.Columns("orderId")}

    dataSet.Tables.AddRange(New DataTable() {customersTable, ordersTable})

    ' remove all tables
    ' check if table can be removed and then
    ' remove it, cannot use a foreach when
    ' removing items from a collection
    Do While (dataSet.Tables.Count > 0)
        Dim table As DataTable = dataSet.Tables(0)
        If (dataSet.Tables.CanRemove(table)) Then
            dataSet.Tables.Remove(table)
        End If
    Loop

Console.WriteLine("dataSet has {0} tables", dataSet.Tables.Count)
End Sub