DataGridView 控件包括 DataGridViewButtonCell 类，该类用于显示具有类似按钮的用户界面 (UI) 的单元格。但 DataGridViewButtonCell 不提供禁用由单元格显示的按钮外观的方式。 

下面的代码示例演示如何自定义 DataGridViewButtonCell 类来显示可以显示为禁用的按钮。本示例定义一个新的单元格类型 DataGridViewDisableButtonCell，它由 DataGridViewButtonCell 派生。此单元格类型提供一个新的 Enabled 属性，可以将该属性设置为 false 来在单元格中绘制禁用的按钮。本示例还定义一个新的列类型 DataGridViewDisableButtonColumn，它显示 DataGridViewDisableButtonCell 对象。为了演示此新单元格类型和列类型，父 DataGridView 中的每个 DataGridViewCheckBoxCell 的当前值确定同一行中 DataGridViewDisableButtonCell 的 Enabled 属性是 true 还是 false。 

首先要在代码中加入下面两个继承类： 

public class DataGridViewDisableButtonColumn : DataGridViewButtonColumn
    {
        public DataGridViewDisableButtonColumn()
        {
            this.CellTemplate = new DataGridViewDisableButtonCell();
        }
    }

    public class DataGridViewDisableButtonCell : DataGridViewButtonCell
    {
        private bool enabledValue;
        public bool Enabled
        {
            get
            {
                return enabledValue;
            }
            set
            {
                enabledValue = value;
            }
        }

        public override object Clone()
        {
            DataGridViewDisableButtonCell cell =
                (DataGridViewDisableButtonCell)base.Clone();
            cell.Enabled = this.Enabled;
            return cell;
        }

        public DataGridViewDisableButtonCell()
        {
            this.enabledValue = true;
        }

        protected override void Paint(Graphics graphics,
            Rectangle clipBounds, Rectangle cellBounds, int rowIndex,
            DataGridViewElementStates elementState, object value,
            object formattedValue, string errorText,
            DataGridViewCellStyle cellStyle,
            DataGridViewAdvancedBorderStyle advancedBorderStyle,
            DataGridViewPaintParts paintParts)
        {
            if (!this.enabledValue)
            {
                if ((paintParts & DataGridViewPaintParts.Background) ==
                    DataGridViewPaintParts.Background)
                {
                    SolidBrush cellBackground =
                        new SolidBrush(cellStyle.BackColor);
                    graphics.FillRectangle(cellBackground, cellBounds);
                    cellBackground.Dispose();
                }

                if ((paintParts & DataGridViewPaintParts.Border) ==
                    DataGridViewPaintParts.Border)
                {
                    PaintBorder(graphics, clipBounds, cellBounds, cellStyle,
                        advancedBorderStyle);
                }
                Rectangle buttonArea = cellBounds;
                Rectangle buttonAdjustment =
                    this.BorderWidths(advancedBorderStyle);
                buttonArea.X += buttonAdjustment.X;
                buttonArea.Y += buttonAdjustment.Y;
                buttonArea.Height -= buttonAdjustment.Height;
                buttonArea.Width -= buttonAdjustment.Width;
                ButtonRenderer.DrawButton(graphics, buttonArea,
                    System.Windows.Forms.VisualStyles.PushButtonState.Disabled);

                if (this.FormattedValue is String)
                {
                    TextRenderer.DrawText(graphics,
                        (string)this.FormattedValue,
                        this.DataGridView.Font,
                        buttonArea, SystemColors.GrayText);
                }
            }
            else
            {
                base.Paint(graphics, clipBounds, cellBounds, rowIndex,
                    elementState, value, formattedValue, errorText,
                    cellStyle, advancedBorderStyle, paintParts);
            }
        }
    }

datagridview的button控件要在代码里面加入： 
如加入编辑按钮： 

DataGridViewDisableButtonColumn btn_ProEdit = new DataGridViewDisableButtonColumn();
            btn_ProEdit.HeaderText = l.ALanuageBinding("gv_Action");
            btn_ProEdit.Text = l.ALanuageBinding("gv_Edit");
            btn_ProEdit.Name = "btn_ProEdit";
            btn_ProEdit.Width = 50;
            btn_ProEdit.UseColumnTextForButtonValue = true;
this.datagridview1.Columns.Add(btn_ProEdit);

禁用： 

DataGridViewDisableButtonCell buttonCell = (DataGridViewDisableButtonCell)dgv_Promotiom.Rows[i].Cells["btn_ProEdit"];

                        buttonCell.Enabled = false;