Just a few days ago, I encountered a problem when opening a exist c++ solution, and the error shows: "An error occurred while creating or opening the C++ browsing database file D:\projects\MyProject\MyProject.sdf. IntelliSense and browsing information will not be available for C++ projects. Ensure that Microsoft SQL Server Compact 3.5 is installed and that no other applications are accessing the file. If this problem persists, delete the file and reopen the solution".

After searching the Internet , I found the recipe for this bug . As for me , downloading and manually installingSQL Server Compact 3.5 SP2remedies the problem. You can find more detail on this page: http://msdn.microsoft.com/en-us/library/ks1ka3t6.aspx